Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis

Autophagy inhibitors are currently being evaluated in clinical trials for the treatment of diverse cancers, largely due to their ability to impede tumor cell survival and metabolic adaptation. More recently, there is growing interest in whether and how modulating autophagy in the host stroma influen...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Rudnick, Jenny A., Monkkonen, Teresa, Mar, Florie A., Barnes, James M., Starobinets, Hanna, Goldsmith, Juliet, Roy, Srirupa, Bustamante Eguiguren, Sofía, Weaver, Valerie M., Debnath, Jayanta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2021
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247603/
https://ncbi.nlm.nih.gov/pubmed/34168038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.345629.120
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