Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B

[Image: see text] A library of monosubstituted chalcones (1–17) bearing electron-donating and electron-withdrawing groups on both aromatic rings were selected. The cell viability on human tumor cell lines was evaluated first. The compounds unable to induce detectable cytotoxicity (1, 13, and 14) wer...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Iacovino, Luca G., Pinzi, Luca, Facchetti, Giorgio, Bortolini, Beatrice, Christodoulou, Michael S., Binda, Claudia, Rastelli, Giulio, Rimoldi, Isabella, Passarella, Daniele, Di Paolo, Maria Luisa, Dalla Via, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274062/
https://ncbi.nlm.nih.gov/pubmed/34262643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.1c00238
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