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Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation

It has been well-established that cancer cells often display altered metabolic profiles, and recent work has concentrated on how cancer cells adapt to serine removal. Serine can be either taken exogenously or synthesized from glucose, and its regulation forms an important mechanism for nutrient inte...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Truman, Jean-Philip, Ruiz, Christian F., Trayssac, Magali, Mao, Cungui, Hannun, Yusuf A., Obeid, Lina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8272629/
https://ncbi.nlm.nih.gov/pubmed/33484475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001814RR
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