Cathelicidin and PMB neutralize endotoxins by multifactorial mechanisms including LPS interaction and targeting of host cell membranes

Antimicrobial peptides (AMPs) contribute to an effective protection against infections. The antibacterial function of AMPs depends on their interactions with microbial membranes and lipids, such as lipopolysaccharide (LPS; endotoxin). Hyperinflammation induced by endotoxin is a key factor in bacteri...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Schromm, Andra B., Paulowski, Laura, Kaconis, Yani, Kopp, Franziska, Koistinen, Max, Donoghue, Annemarie, Keese, Susanne, Nehls, Christian, Wernecke, Julia, Garidel, Patrick, Sevcsik, Eva, Lohner, Karl, Sanchez-Gomez, Susana, Martinez-de-Tejada, Guillermo, Brandenburg, Klaus, Brameshuber, Mario, Schütz, Gerhard J., Andrä, Jörg, Gutsmann, Thomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271772/
https://ncbi.nlm.nih.gov/pubmed/34183393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2101721118
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