Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms

Microbial biofilms are involved in a number of infections that cannot be cured, as microbes in biofilms resist host immune defenses and antibiotic therapies. With no strict biofilm-antibiotic in the current pipelines, there is an unmet need for drug candidates that enable the current antibiotics to...

Full description

Saved in:
Bibliographic Details
Published in:NPJ Biofilms Microbiomes
Main Authors: Andersen, Jens Bo, Hultqvist, Louise Dahl, Jansen, Charlotte Uldahl, Jakobsen, Tim Holm, Nilsson, Martin, Rybtke, Morten, Uhd, Jesper, Fritz, Blaine Gabriel, Seifert, Roland, Berthelsen, Jens, Nielsen, Thomas Eiland, Qvortrup, Katrine, Givskov, Michael, Tolker-Nielsen, Tim
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271024/
https://ncbi.nlm.nih.gov/pubmed/34244523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41522-021-00225-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items