Attenuated asthma phenotype in mice with a fetal-like antigen receptor repertoire

We hypothesized that the scarcity of N-nucleotides might contribute to the inability of the neonate to mount a robust allergic immune response. To test this, we used terminal deoxyribunucleotidyl Transferase deficient (TdT(−/−)) mice, which express “fetal-like” T cell receptor and immunoglobulin rep...

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Publicat a:Sci Rep
Autors principals: Stutz, Regine, Meyer, Christopher, Kaiser, Elisabeth, Goedicke-Fritz, Sybelle, Schroeder, Harry W., Bals, Robert, Haertel, Christoph, Rogosch, Tobias, Kerzel, Sebastian, Zemlin, Michael
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270943/
https://ncbi.nlm.nih.gov/pubmed/34244568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93553-6
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