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Composition of the immunoglobulin classic antigen-binding site regulates allergic airway inflammation in a murine model of experimental asthma
BACKGROUND: When bound to mast cell FcεRI, IgE serves as antigen receptor for allergic reactions, permitting specific identification of the allergen. Although the core of the classic antigen-binding site is heavy chain complementarity determining region 3 (CDR-H3), recent studies suggest that allerg...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681526/ https://ncbi.nlm.nih.gov/pubmed/19220320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2008.03178.x |
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