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Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides

Isopeptide crosslinked proteins can be the product of transglutaminase or of exposure to organophosphorus toxicants (OP). Transglutaminase links glutamine to lysine with loss of ammonia. OP toxicants induce a link between glutamic acid and lysine with loss of water. Our goal was to establish criteri...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Schopfer, Lawrence M., Onder, Seda, Lockridge, Oksana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270460/
https://ncbi.nlm.nih.gov/pubmed/34242352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254450
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