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Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides

Isopeptide crosslinked proteins can be the product of transglutaminase or of exposure to organophosphorus toxicants (OP). Transglutaminase links glutamine to lysine with loss of ammonia. OP toxicants induce a link between glutamic acid and lysine with loss of water. Our goal was to establish criteri...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schopfer, Lawrence M., Onder, Seda, Lockridge, Oksana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270460/
https://ncbi.nlm.nih.gov/pubmed/34242352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254450
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