Protein Aggregation Patterns Inform about Breast Cancer Response to Antiestrogens and Reveal the RNA Ligase RTCB as Mediator of Acquired Tamoxifen Resistance

SIMPLE SUMMARY: Acquired resistance to antiestrogenic therapy remains the major obstacle to curing luminal subtype breast cancer. While current treatment in acquired endocrine-resistant settings includes combined therapy with receptor tyrosine kinase or cyclin-dependent kinase inhibitors, progressio...

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Bibliografski detalji
Izdano u:Cancers (Basel)
Glavni autori: Direito, Inês, Monteiro, Liliana, Melo, Tânia, Figueira, Daniela, Lobo, João, Enes, Vera, Moura, Gabriela, Henrique, Rui, Santos, Manuel A. S., Jerónimo, Carmen, Amado, Francisco, Fardilha, Margarida, Helguero, Luisa A.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269126/
https://ncbi.nlm.nih.gov/pubmed/34206811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133195
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