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RAB10 Interacts with ABCB4 and Regulates Its Intracellular Traffic

ABCB4 (ATP-binding cassette subfamily B member 4) is an ABC transporter expressed at the canalicular membrane of hepatocytes where it ensures phosphatidylcholine secretion into bile. Genetic variations of ABCB4 are associated with several rare cholestatic diseases. The available treatments are not e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Ben Saad, Amel, Vauthier, Virginie, Lapalus, Martine, Mareux, Elodie, Bennana, Evangéline, Durand-Schneider, Anne-Marie, Bruneau, Alix, Delaunay, Jean-Louis, Gonzales, Emmanuel, Housset, Chantal, Aït-Slimane, Tounsia, Guillonneau, François, Jacquemin, Emmanuel, Falguières, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268348/
https://ncbi.nlm.nih.gov/pubmed/34209301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22137087
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