A PDZ-Like Motif in the Biliary Transporter ABCB4 Interacts with the Scaffold Protein EBP50 and Regulates ABCB4 Cell Surface Expression

ABCB4/MDR3, a member of the ABC superfamily, is an ATP-dependent phosphatidylcholine translocator expressed at the canalicular membrane of hepatocytes. Defects in the ABCB4 gene are associated with rare biliary diseases. It is essential to understand the mechanisms of its canalicular membrane expres...

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Veröffentlicht in:PLoS One
Hauptverfasser: Venot, Quitterie, Delaunay, Jean-Louis, Fouassier, Laura, Delautier, Danièle, Falguières, Thomas, Housset, Chantal, Maurice, Michèle, Aït-Slimane, Tounsia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720445/
https://ncbi.nlm.nih.gov/pubmed/26789121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146962
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