Young Adult LEW.1WR1 Rats Develop Dysregulated Islet Function and Impaired Liver Insulin Responses

Obesity in humans can lead to metabolic problems such as glucose intolerance and insulin resistance, which may result from pancreatic islet dysregulation and reduced insulin sensitivity in the liver. LEW.1WR1 (1WR1) rats became more glucose intolerant than LEW/SsNHsd (SsNHsd) rats after 12 weeks on...

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Pubblicato in:J Endocr Soc
Autori principali: Wilkerson-Vidal, Quiana C, Collins, Genoah L, Fowler, Evann, Wimalarathne, Madushika M, Mercado, Luis D, Gibson, Helen, Martin, Sidney C, Love-Rutledge, Sharifa Tahirah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Diabetes Mellitus and Glucose Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265834/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.909
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