Young Adult LEW.1WR1 Rats, a Model of Liver FAT10 Overexpression, Develop Insulin Resistance and Fatty Liver With Age

As human lifespan increases, comorbid conditions that impact quality of life have become a serious problem. FAT10 has been identified as a gene that when knocked out, improves age associated metabolic dysfunctions and increased longevity in mice (1). There is increased Fat10 expression in the liver...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Wimalarathne, Madushika M, Mercado, Luis D, Vidal, Quiana C Wilkerson, Wolfsberger, James, McConnell, Victoria J, Vogler, Bernhard, Love-Rutledge, Sharifa Tahirah
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Genetics and Development (including Gene Regulation)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090564/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1051
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