Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Nonmalignant Clonal Hematopoiesis

Genetic mutations associated with acute myeloid leukemia (AML) also occur in age-related clonal hematopoiesis, often in the same individual. This makes confident assignment of detected variants to malignancy challenging. The issue is particularly crucial for AML posttreatment measurable residual dis...

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書誌詳細
出版年:Blood Cancer Discov
主要な著者: Dillon, Laura W., Ghannam, Jack, Nosiri, Chidera, Gui, Gege, Goswami, Meghali, Calvo, Katherine R., Lindblad, Katherine E., Oetjen, Karolyn A., Wilkerson, Matthew D., Soltis, Anthony R., Sukumar, Gauthaman, Dalgard, Clifton L., Thompson, Julie, Valdez, Janet, DeStefano, Christin B., Lai, Catherine, Sciambi, Adam, Durruthy-Durruthy, Robert, Llanso, Aaron, Gulati, Saurabh, Wang, Shu, Ooi, Aik, Dagur, Pradeep K., McCoy, J. Philip, Burr, Patrick, Li, Yuesheng, Hourigan, Christopher S.
フォーマット: Artigo
言語:Inglês
出版事項: American Association for Cancer Research 2021
主題:
Research Brief
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265308/
https://ncbi.nlm.nih.gov/pubmed/34258102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-21-0046
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