Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Nonmalignant Clonal Hematopoiesis

Genetic mutations associated with acute myeloid leukemia (AML) also occur in age-related clonal hematopoiesis, often in the same individual. This makes confident assignment of detected variants to malignancy challenging. The issue is particularly crucial for AML posttreatment measurable residual dis...

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Detalhes bibliográficos
Publicado no:Blood Cancer Discov
Main Authors: Dillon, Laura W., Ghannam, Jack, Nosiri, Chidera, Gui, Gege, Goswami, Meghali, Calvo, Katherine R., Lindblad, Katherine E., Oetjen, Karolyn A., Wilkerson, Matthew D., Soltis, Anthony R., Sukumar, Gauthaman, Dalgard, Clifton L., Thompson, Julie, Valdez, Janet, DeStefano, Christin B., Lai, Catherine, Sciambi, Adam, Durruthy-Durruthy, Robert, Llanso, Aaron, Gulati, Saurabh, Wang, Shu, Ooi, Aik, Dagur, Pradeep K., McCoy, J. Philip, Burr, Patrick, Li, Yuesheng, Hourigan, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2021
Assuntos:
Research Brief
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265308/
https://ncbi.nlm.nih.gov/pubmed/34258102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-21-0046
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