Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Nonmalignant Clonal Hematopoiesis

Genetic mutations associated with acute myeloid leukemia (AML) also occur in age-related clonal hematopoiesis, often in the same individual. This makes confident assignment of detected variants to malignancy challenging. The issue is particularly crucial for AML posttreatment measurable residual dis...

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Bibliografiset tiedot
Julkaisussa:Blood Cancer Discov
Päätekijät: Dillon, Laura W., Ghannam, Jack, Nosiri, Chidera, Gui, Gege, Goswami, Meghali, Calvo, Katherine R., Lindblad, Katherine E., Oetjen, Karolyn A., Wilkerson, Matthew D., Soltis, Anthony R., Sukumar, Gauthaman, Dalgard, Clifton L., Thompson, Julie, Valdez, Janet, DeStefano, Christin B., Lai, Catherine, Sciambi, Adam, Durruthy-Durruthy, Robert, Llanso, Aaron, Gulati, Saurabh, Wang, Shu, Ooi, Aik, Dagur, Pradeep K., McCoy, J. Philip, Burr, Patrick, Li, Yuesheng, Hourigan, Christopher S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for Cancer Research 2021
Aiheet:
Research Brief
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265308/
https://ncbi.nlm.nih.gov/pubmed/34258102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-21-0046
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