Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Nonmalignant Clonal Hematopoiesis

Genetic mutations associated with acute myeloid leukemia (AML) also occur in age-related clonal hematopoiesis, often in the same individual. This makes confident assignment of detected variants to malignancy challenging. The issue is particularly crucial for AML posttreatment measurable residual dis...

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Dettagli Bibliografici
Pubblicato in:Blood Cancer Discov
Autori principali: Dillon, Laura W., Ghannam, Jack, Nosiri, Chidera, Gui, Gege, Goswami, Meghali, Calvo, Katherine R., Lindblad, Katherine E., Oetjen, Karolyn A., Wilkerson, Matthew D., Soltis, Anthony R., Sukumar, Gauthaman, Dalgard, Clifton L., Thompson, Julie, Valdez, Janet, DeStefano, Christin B., Lai, Catherine, Sciambi, Adam, Durruthy-Durruthy, Robert, Llanso, Aaron, Gulati, Saurabh, Wang, Shu, Ooi, Aik, Dagur, Pradeep K., McCoy, J. Philip, Burr, Patrick, Li, Yuesheng, Hourigan, Christopher S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for Cancer Research 2021
Soggetti:
Research Brief
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265308/
https://ncbi.nlm.nih.gov/pubmed/34258102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-21-0046
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