OTEH-2. High-dimensional analysis of spatial immune cell heterogeneity in glioblastoma reveals differences between contrast-enhancing and non-contrast-enhancing tumor rims

BACKGROUND: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. GBM remains an incurable disease, with a median survival ~20 months. Complex intercellular interactions within the tumor microenvironment and spatial heterogeneity have challenged and impeded therapeutic effic...

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Veröffentlicht in:Neurooncol Adv
Hauptverfasser: Watson, Dionysios C, Bayik, Defne, Grabowski, Matthew, Ahluwalia, Manmeet, Mohammadi, Alireza, Lathia, Justin D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264919/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.041
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