WOMAN-PharmacoTXA trial: Study protocol for a randomised controlled trial to assess the pharmacokinetics and pharmacodynamics of intramuscular, intravenous and oral administration of tranexamic acid in women giving birth by caesarean section

Background: Intravenous tranexamic acid (TXA) within 3 hours of birth significantly reduces death due to bleeding in women with postpartum haemorrhage (PPH). Most PPH deaths occur in the first hours after giving birth and treatment delay decreases survival.  One barrier to rapid TXA treatment is the...

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Detalhes bibliográficos
Publicado no:Wellcome Open Res
Main Authors: Arribas, Monica, Roberts, Ian, Chaudhri, Rizwana, Geer, Amber, Prowse, Danielle, Lubeya, Mwansa Ketty, Kayani, Aasia, Javaid, Kiran, Grassin-Delyle, Stanislas, Shakur-Still, Haleema
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2021
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264807/
https://ncbi.nlm.nih.gov/pubmed/34250266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.16884.1
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