WOMAN-PharmacoTXA trial: Study protocol for a randomised controlled trial to assess the pharmacokinetics and pharmacodynamics of intramuscular, intravenous and oral administration of tranexamic acid in women giving birth by caesarean section

Background: Intravenous tranexamic acid (TXA) within 3 hours of birth significantly reduces death due to bleeding in women with postpartum haemorrhage (PPH). Most PPH deaths occur in the first hours after giving birth and treatment delay decreases survival.  One barrier to rapid TXA treatment is the...

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Publicado en:Wellcome Open Res
Autores principales: Arribas, Monica, Roberts, Ian, Chaudhri, Rizwana, Geer, Amber, Prowse, Danielle, Lubeya, Mwansa Ketty, Kayani, Aasia, Javaid, Kiran, Grassin-Delyle, Stanislas, Shakur-Still, Haleema
Formato: Artigo
Lenguaje:Inglês
Publicado: F1000 Research Limited 2021
Materias:
Study Protocol
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264807/
https://ncbi.nlm.nih.gov/pubmed/34250266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.16884.1
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