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α-Particle-induced DNA damage tracks in peripheral blood mononuclear cells of [(223)Ra]RaCl(2)-treated prostate cancer patients
PURPOSE: One therapy option for prostate cancer patients with bone metastases is the use of [(223)Ra]RaCl(2). The α-emitter (223)Ra creates DNA damage tracks along α-particle trajectories (α-tracks) in exposed cells that can be revealed by immunofluorescent staining of γ-H2AX+53BP1 DNA double-strand...
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| Veröffentlicht in: | Eur J Nucl Med Mol Imaging |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8263441/ https://ncbi.nlm.nih.gov/pubmed/33537837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-05170-6 |
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