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DNA damage in leukocytes after internal ex-vivo irradiation of blood with the α-emitter Ra-223
Irradiation with high linear energy transfer α-emitters, like the clinically used Ra-223 dichloride, severely damages cells and induces complex DNA damage including closely spaced double-strand breaks (DSBs). As the hematopoietic system is an organ-at-risk for the treatment, knowledge about Ra-223-i...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5797089/ https://ncbi.nlm.nih.gov/pubmed/29396412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20364-7 |
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