Inhibition of Chitinase-3-like-1 by K284-6111 Reduces Atopic Skin Inflammation via Repressing Lactoferrin

Chitinase-3-like-1 (CHI3L1) is known to induce inflammation in the progression of allergic diseases. Previous our studies revealed that 2-({3-[2-(1-cyclohexen-1-yl)ethyl]-6,7-dimethoxy-4-oxo-3,4-dihydro-2-quinazolinyl}sulfanyl)-N-(4-ethylphenyl)butanamide (K284-6111; K284), the CHI3L1 inhibiting com...

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Detalhes bibliográficos
Publicado no:Immune Netw
Main Authors: Jeon, Seong Hee, Lee, Yong Sun, Yeo, In Jun, Lee, Hee Pom, Yoon, Jaesuk, Son, Dong Ju, Han, Sang-Bae, Hong, Jin Tae
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Immunologists 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263211/
https://ncbi.nlm.nih.gov/pubmed/34277112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2021.21.e22
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