K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression

BACKGROUND: Alzheimer’s disease, which is pathologically characterized by an excessive accumulation of amyloid beta (Aβ) fibrils, is a degenerative brain disease and the most common cause of dementia. In a previous study, it was reported that an increased level of CHI3L1 in plasma was found in AD pa...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Neuroinflammation
Autors principals: Choi, Ji Yeon, Yeo, In Jun, Kim, Ki Cheon, Choi, Won Rack, Jung, Jae-Kyung, Han, Sang-Bae, Hong, Jin Tae
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087013/
https://ncbi.nlm.nih.gov/pubmed/30098604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1269-3
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars