Genetic Variation in PFKFB3 Impairs Antifungal Immunometabolic Responses and Predisposes to Invasive Pulmonary Aspergillosis

Activation of immune cells in response to fungal infection involves the reprogramming of their cellular metabolism to support antimicrobial effector functions. Although metabolic pathways such as glycolysis are known to represent critical regulatory nodes in antifungal immunity, it remains undetermi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:mBio
Hlavní autoři: Gonçalves, Samuel M., Antunes, Daniela, Leite, Luis, Mercier, Toine, ter Horst, Rob, Vieira, Joana, Espada, Eduardo, Pinho Vaz, Carlos, Branca, Rosa, Campilho, Fernando, Freitas, Fátima, Ligeiro, Dário, Marques, António, van de Veerdonk, Frank L., Joosten, Leo A. B., Lagrou, Katrien, Maertens, Johan, Netea, Mihai G., Lacerda, João F., Campos, António, Cunha, Cristina, Carvalho, Agostinho
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263003/
https://ncbi.nlm.nih.gov/pubmed/34044589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00369-21
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky