Genetic Variation in PFKFB3 Impairs Antifungal Immunometabolic Responses and Predisposes to Invasive Pulmonary Aspergillosis

Activation of immune cells in response to fungal infection involves the reprogramming of their cellular metabolism to support antimicrobial effector functions. Although metabolic pathways such as glycolysis are known to represent critical regulatory nodes in antifungal immunity, it remains undetermi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:mBio
Κύριοι συγγραφείς: Gonçalves, Samuel M., Antunes, Daniela, Leite, Luis, Mercier, Toine, ter Horst, Rob, Vieira, Joana, Espada, Eduardo, Pinho Vaz, Carlos, Branca, Rosa, Campilho, Fernando, Freitas, Fátima, Ligeiro, Dário, Marques, António, van de Veerdonk, Frank L., Joosten, Leo A. B., Lagrou, Katrien, Maertens, Johan, Netea, Mihai G., Lacerda, João F., Campos, António, Cunha, Cristina, Carvalho, Agostinho
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2021
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263003/
https://ncbi.nlm.nih.gov/pubmed/34044589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00369-21
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