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The Toxoplasma Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain

Toxoplasmic encephalitis can develop in individuals infected with the protozoan parasite Toxoplasma gondii and is typified by parasite replication and inflammation within the brain. Patients often present with seizures, but the parasite genes and host pathways involved in seizure development and/or...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Glausen, Taylor G., Carrillo, Gabriela L., Jin, Richard M., Boyle, Jon P., Saeij, Jeroen P. J., Wohlfert, Elizabeth A., Fox, Michael A., Blader, Ira J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262954/
https://ncbi.nlm.nih.gov/pubmed/34154412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01331-21
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