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Comparative Genomics Identifies Putative Interspecies Mechanisms Underlying Crbn-Sall4-Linked Thalidomide Embryopathy

The identification of thalidomide–Cereblon-induced SALL4 degradation has brought new understanding for thalidomide embryopathy (TE) differences across species. Some questions, however, regarding species variability, still remain. The aim of this study was to detect sequence divergences between speci...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Kowalski, Thayne Woycinck, Caldas-Garcia, Gabriela Barreto, Gomes, Julia do Amaral, Fraga, Lucas Rosa, Schuler-Faccini, Lavínia, Recamonde-Mendoza, Mariana, Paixão-Côrtes, Vanessa Rodrigues, Vianna, Fernanda Sales Luiz
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262662/
https://ncbi.nlm.nih.gov/pubmed/34249098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.680217
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