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CRL4-Cereblon complex in Thalidomide Embryopathy: a translational investigation

The Cereblon-CRL4 complex has been studied predominantly with regards to thalidomide treatment of multiple myeloma. Nevertheless, the role of Cereblon-CRL4 in Thalidomide Embryopathy (TE) is still not understood. Not all embryos exposed to thalidomide develop TE, hence here we evaluate the role of t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kowalski, Thayne Woycinck, Gomes, Julia do Amaral, Garcia, Gabriela Barreto Caldas, Fraga, Lucas Rosa, Paixao-Cortes, Vanessa Rodrigues, Recamonde-Mendoza, Mariana, Sanseverino, Maria Teresa Vieira, Schuler-Faccini, Lavinia, Vianna, Fernanda Sales Luiz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972723/
https://ncbi.nlm.nih.gov/pubmed/31964914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57512-x
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