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New Findings in eNOS gene and Thalidomide Embryopathy Suggest pre-transcriptional effect variants as susceptibility factors

Antiangiogenic properties of thalidomide have created an interest in the use of the drug in treatment of cancer. However, thalidomide is responsible for thalidomide embryopathy (TE). A lack of knowledge regarding the mechanisms of thalidomide teratogenesis acts as a barrier in the aim to synthesize...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kowalski, Thayne Woycinck, Fraga, Lucas Rosa, Tovo-Rodrigues, Luciana, Sanseverino, Maria Teresa Vieira, Hutz, Mara Helena, Schuler-Faccini, Lavínia, Vianna, Fernanda Sales Luiz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804217/
https://ncbi.nlm.nih.gov/pubmed/27004986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23404
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