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New Findings in eNOS gene and Thalidomide Embryopathy Suggest pre-transcriptional effect variants as susceptibility factors

Antiangiogenic properties of thalidomide have created an interest in the use of the drug in treatment of cancer. However, thalidomide is responsible for thalidomide embryopathy (TE). A lack of knowledge regarding the mechanisms of thalidomide teratogenesis acts as a barrier in the aim to synthesize...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kowalski, Thayne Woycinck, Fraga, Lucas Rosa, Tovo-Rodrigues, Luciana, Sanseverino, Maria Teresa Vieira, Hutz, Mara Helena, Schuler-Faccini, Lavínia, Vianna, Fernanda Sales Luiz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804217/
https://ncbi.nlm.nih.gov/pubmed/27004986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23404
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