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New Findings in eNOS gene and Thalidomide Embryopathy Suggest pre-transcriptional effect variants as susceptibility factors

Antiangiogenic properties of thalidomide have created an interest in the use of the drug in treatment of cancer. However, thalidomide is responsible for thalidomide embryopathy (TE). A lack of knowledge regarding the mechanisms of thalidomide teratogenesis acts as a barrier in the aim to synthesize...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Kowalski, Thayne Woycinck, Fraga, Lucas Rosa, Tovo-Rodrigues, Luciana, Sanseverino, Maria Teresa Vieira, Hutz, Mara Helena, Schuler-Faccini, Lavínia, Vianna, Fernanda Sales Luiz
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804217/
https://ncbi.nlm.nih.gov/pubmed/27004986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23404
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