Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle

Aberrant lipid metabolism promotes the development of skeletal muscle insulin resistance, but the exact identity of lipid-mediated mechanisms relevant to human obesity remains unclear. A comprehensive lipidomic analysis of primary myocytes from individuals who were insulin-sensitive and lean (LN) or...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ferrara, Patrick J., Rong, Xin, Maschek, J. Alan, Verkerke, Anthony R.P., Siripoksup, Piyarat, Song, Haowei, Green, Thomas D., Krishnan, Karthickeyan C., Johnson, Jordan M., Turk, John, Houmard, Joseph A., Lusis, Aldons J., Drummond, Micah J., McClung, Joseph M., Cox, James E., Shaikh, Saame Raza, Tontonoz, Peter, Holland, William L., Funai, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262507/
https://ncbi.nlm.nih.gov/pubmed/33591957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI135963
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