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Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy
Muscular dystrophy is accompanied by a reduction in activity of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) that contributes to abnormal Ca(2+) homeostasis in sarco/endoplasmic reticulum (SR/ER). Recent findings suggest that skeletal muscle fatty acid synthase (FAS) modulates SERCA activity an...
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Publicado no: | Biochim Biophys Acta |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619134/ https://ncbi.nlm.nih.gov/pubmed/26361872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2015.09.001 |
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