Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy

Muscular dystrophy is accompanied by a reduction in activity of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) that contributes to abnormal Ca(2+) homeostasis in sarco/endoplasmic reticulum (SR/ER). Recent findings suggest that skeletal muscle fatty acid synthase (FAS) modulates SERCA activity an...

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Publicat a:Biochim Biophys Acta
Autors principals: Paran, Christopher W., Zou, Kai, Ferrara, Patrick J., Song, Haowei, Turk, John, Funai, Katsuhiko
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619134/
https://ncbi.nlm.nih.gov/pubmed/26361872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2015.09.001
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