Assessment of kidney proximal tubular secretion in critical illness

BACKGROUND: Serum creatinine concentrations (SCrs) are used to determine the presence and severity of acute kidney injury (AKI). SCr is primarily eliminated by glomerular filtration; however, most mechanisms of AKI in critical illness involve kidney proximal tubules, where tubular secretion occurs....

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Bhatraju, Pavan K., Chai, Xin-Ya, Sathe, Neha A., Ruzinski, John, Siew, Edward D., Himmelfarb, Jonathan, Hoofnagle, Andrew N., Wurfel, Mark M., Kestenbaum, Bryan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262320/
https://ncbi.nlm.nih.gov/pubmed/33886506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.145514
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