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Diurnal and Long-Term Variation in Plasma Concentrations and Renal Clearances of Circulating Markers of Kidney Proximal Tubular Secretion

BACKGROUND: The renal proximal tubule is essential for removing organic solutes and exogenous medications from the circulation. We evaluated diurnal, prandial, and long-term biological variation of four candidate endogenous markers of proximal tubular secretion. METHODS: We used liquid chromatograph...

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Detalhes bibliográficos
Publicado no:Clin Chem
Main Authors: Rivara, Matthew B., Zelnick, Leila R., Hoofnagle, Andrew N., Newitt, Rick, Tracy, Russell P., Kratz, Mario, Weigle, David S., Kestenbaum, Bryan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564449/
https://ncbi.nlm.nih.gov/pubmed/28188231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2016.260117
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