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Alterations of Proximal Tubular Secretion in Autosomal Dominant Polycystic Kidney Disease

BACKGROUND AND OBJECTIVES: In autosomal dominant polycystic kidney disease (ADPKD), the GFR often remains normal despite significant nephron loss. Proximal tubular secretory clearance may be reduced in ADPKD before detectable changes in GFR. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We used...

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Detalhes bibliográficos
Publicado no:Clin J Am Soc Nephrol
Main Authors: Wang, Ke, Zelnick, Leila R., Chen, Yan, Hoofnagle, Andrew N., Watnick, Terry, Seliger, Stephen, Kestenbaum, Bryan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946073/
https://ncbi.nlm.nih.gov/pubmed/31628117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05610519
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