Alterations of Proximal Tubular Secretion in Autosomal Dominant Polycystic Kidney Disease

BACKGROUND AND OBJECTIVES: In autosomal dominant polycystic kidney disease (ADPKD), the GFR often remains normal despite significant nephron loss. Proximal tubular secretory clearance may be reduced in ADPKD before detectable changes in GFR. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We used...

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Bibliographic Details
Published in:Clin J Am Soc Nephrol
Main Authors: Wang, Ke, Zelnick, Leila R., Chen, Yan, Hoofnagle, Andrew N., Watnick, Terry, Seliger, Stephen, Kestenbaum, Bryan
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946073/
https://ncbi.nlm.nih.gov/pubmed/31628117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05610519
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