TIGIT modulates sepsis-induced immune dysregulation in mice with preexisting malignancy

TIGIT is a recently identified coinhibitory receptor that is upregulated in the setting of cancer and functionally contributes to the impairment of antitumor immunity. However, its role during sepsis is unknown. Because patients with cancer are 10 times more likely to die of sepsis than previously h...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Zhang, Wenxiao, Anyalebechi, Jerome C., Ramonell, Kimberly M., Chen, Ching-wen, Xie, Jianfeng, Liang, Zhe, Chihade, Deena B., Otani, Shunsuke, Coopersmith, Craig M., Ford, Mandy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262279/
https://ncbi.nlm.nih.gov/pubmed/34100383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139823
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