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NAD(+) homeostasis in human health and disease

Depletion of nicotinamide adenine dinucleotide (NAD(+)), a central redox cofactor and the substrate of key metabolic enzymes, is the causative factor of a number of inherited and acquired diseases in humans. Primary deficiencies of NAD(+) homeostasis are the result of impaired biosynthesis, while se...

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Detalles Bibliográficos
Publicado en:EMBO Mol Med
Main Authors: Zapata‐Pérez, Rubén, Wanders, Ronald J A, van Karnebeek, Clara D M, Houtkooper, Riekelt H
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261484/
https://ncbi.nlm.nih.gov/pubmed/34041853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202113943
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