DAPT suppresses proliferation and migration of hepatocellular carcinoma by regulating the extracellular matrix and inhibiting the Hes1/PTEN/AKT/mTOR signaling pathway

BACKGROUND: The aim of the present study was to investigate the antitumor properties of N-(N-[3,5-difluorophenacetyl]-1-alanyl)-S-phenylglycine t-butyl ester (DAPT) against hepatocellular carcinoma (HCC), as well as the underlying mechanism. METHODS: Immunohistochemistry and quantitative reverse tra...

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Detalhes bibliográficos
Publicado no:J Gastrointest Oncol
Main Authors: Qiu, Kaijie, Ma, Chenyang, Lu, Lingchao, Wang, Jie, Chen, Baiwen, Mao, Haixiang, Wang, Yanmin, Wang, Haibiao
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261317/
https://ncbi.nlm.nih.gov/pubmed/34295560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo-21-235
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