MicroRNA-10 negatively regulates inflammation in diabetic kidney via targeting activation of the NLRP3 inflammasome

NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome activation has emerged as a central mediator of kidney inflammation in diabetic kidney disease (DKD). However, the mechanism underlying this activation in DKD remains poorly defined. In this study, we found that kidney-enriched m...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Ding, Hanying, Li, Jinxiang, Li, Yang, Yang, Minliang, Nie, Sheng, Zhou, Miaomiao, Zhou, Zhanmei, Yang, Xiaobing, Liu, Youhua, Hou, Fan Fan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261077/
https://ncbi.nlm.nih.gov/pubmed/33744467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.03.012
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