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Systemic Administration of Tempol Attenuates the Cardiorespiratory Depressant Effects of Fentanyl

Fentanyl is a high-potency opioid receptor agonist that elicits profound analgesia and suppression of breathing in humans and animals. To date, there is limited evidence as to whether changes in oxidant stress are important factors in any of the actions of acutely administered fentanyl. This study d...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Baby, Santhosh, Gruber, Ryan, Discala, Joseph, Puskovic, Veljko, Jose, Nijo, Cheng, Feixiong, Jenkins, Michael, Seckler, James, Lewis, Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260831/
https://ncbi.nlm.nih.gov/pubmed/34248639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.690407
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