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Glutathione ethyl ester reverses the deleterious effects of fentanyl on ventilation and arterial blood-gas chemistry while prolonging fentanyl-induced analgesia

There is an urgent need to develop novel compounds that prevent the deleterious effects of opioids such as fentanyl on minute ventilation while, if possible, preserving the analgesic actions of the opioids. We report that L-glutathione ethyl ester (GSHee) may be such a novel compound. In this study,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Jenkins, Michael W., Khalid, Faiza, Baby, Santhosh M., May, Walter J., Young, Alex P., Bates, James N., Cheng, Feixiong, Seckler, James M., Lewis, Stephen J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997982/
https://ncbi.nlm.nih.gov/pubmed/33772077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86458-x
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