Systemic Administration of Tempol Attenuates the Cardiorespiratory Depressant Effects of Fentanyl

Fentanyl is a high-potency opioid receptor agonist that elicits profound analgesia and suppression of breathing in humans and animals. To date, there is limited evidence as to whether changes in oxidant stress are important factors in any of the actions of acutely administered fentanyl. This study d...

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Vydáno v:Front Pharmacol
Hlavní autoři: Baby, Santhosh, Gruber, Ryan, Discala, Joseph, Puskovic, Veljko, Jose, Nijo, Cheng, Feixiong, Jenkins, Michael, Seckler, James, Lewis, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260831/
https://ncbi.nlm.nih.gov/pubmed/34248639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.690407
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