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Structural basis of the stereoselective formation of the spirooxindole ring in the biosynthesis of citrinadins
Prenylated indole alkaloids featuring spirooxindole rings possess a 3R or 3S carbon stereocenter, which determines the bioactivities of these compounds. Despite the stereoselective advantages of spirooxindole biosynthesis compared with those of organic synthesis, the biocatalytic mechanism for contr...
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| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8260726/ https://ncbi.nlm.nih.gov/pubmed/34230497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24421-0 |
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