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Uncoupling protein-1 expression does not protect mice from diet-induced obesity

We studied the metabolic phenotype of a novel Ucp1-LUC-iRFP713 knock-in reporter gene mouse model originally generated to monitor endogenous Ucp1 gene expression. Both reporter mice and reporter cells reliably reflected Ucp1 gene expression in vivo and in vitro. We here report an unexpected reductio...

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Détails bibliographiques
Publié dans:Am J Physiol Endocrinol Metab
Auteurs principaux: Wang, Hui, Willershäuser, Monja, Li, Yongguo, Fromme, Tobias, Schnabl, Katharina, Bast-Habersbrunner, Andrea, Ramisch, Samira, Mocek, Sabine, Klingenspor, Martin
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260371/
https://ncbi.nlm.nih.gov/pubmed/33252252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00285.2020
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