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Uncoupling protein-1 expression does not protect mice from diet-induced obesity

We studied the metabolic phenotype of a novel Ucp1-LUC-iRFP713 knock-in reporter gene mouse model originally generated to monitor endogenous Ucp1 gene expression. Both reporter mice and reporter cells reliably reflected Ucp1 gene expression in vivo and in vitro. We here report an unexpected reductio...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Wang, Hui, Willershäuser, Monja, Li, Yongguo, Fromme, Tobias, Schnabl, Katharina, Bast-Habersbrunner, Andrea, Ramisch, Samira, Mocek, Sabine, Klingenspor, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260371/
https://ncbi.nlm.nih.gov/pubmed/33252252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00285.2020
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