Uncoupling protein-1 expression does not protect mice from diet-induced obesity

We studied the metabolic phenotype of a novel Ucp1-LUC-iRFP713 knock-in reporter gene mouse model originally generated to monitor endogenous Ucp1 gene expression. Both reporter mice and reporter cells reliably reflected Ucp1 gene expression in vivo and in vitro. We here report an unexpected reductio...

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Foilsithe in:Am J Physiol Endocrinol Metab
Main Authors: Wang, Hui, Willershäuser, Monja, Li, Yongguo, Fromme, Tobias, Schnabl, Katharina, Bast-Habersbrunner, Andrea, Ramisch, Samira, Mocek, Sabine, Klingenspor, Martin
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2021
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260371/
https://ncbi.nlm.nih.gov/pubmed/33252252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00285.2020
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