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Metabolic responses to intermittent hypoxia are regulated by sex and estradiol in mice

The roles of sex and sex-hormones on the metabolic consequences of intermittent hypoxia (IH, a reliable model of sleep apnea) are unknown. We used intact male or female mice and ovariectomized (OVX) females treated with vehicle (Veh) or estradiol (E(2)) and exposed to normoxia (Nx) or IH (6% O(2), 1...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Marcouiller, François, Jochmans-Lemoine, Alexandra, Ganouna-Cohen, Gauthier, Mouchiroud, Mathilde, Laplante, Mathieu, Marette, André, Bairam, Aida, Joseph, Vincent
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260369/
https://ncbi.nlm.nih.gov/pubmed/33284090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00272.2020
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