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Roles of oestradiol receptor alpha and beta against hypertension and brain mitochondrial dysfunction under intermittent hypoxia in female rats.

AIM: Chronic intermittent hypoxia (CIH) induces systemic (hypertension) and central (mitochondrial dysfunction underlying cognitive deficits). We hypothesized that agonists of oestradiol receptors (ER) α and β prevent CIH-induced hypertension and brain mitochondrial dysfunction. METHODS: Ovariectomi...

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Detalhes bibliográficos
Publicado no:Acta Physiol (Oxf)
Main Authors: Laouafa, Sofien, Roussel, Damien, Marcouiller, François, Soliz, Jorge, Gozal, David, Bairam, Aida, Joseph, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590630/
https://ncbi.nlm.nih.gov/pubmed/30635990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.13255
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